diff --git a/homeassistant/components/knx/__init__.py b/homeassistant/components/knx/__init__.py
index 5c3051978f..8031c41aa4 100644
--- a/homeassistant/components/knx/__init__.py
+++ b/homeassistant/components/knx/__init__.py
@@ -20,6 +20,7 @@ from xknx.telegram.address import (
     parse_device_group_address,
 )
 from xknx.telegram.apci import GroupValueRead, GroupValueResponse, GroupValueWrite
+from xknx_custom_panel import get_knx_ui
 
 from homeassistant.config_entries import ConfigEntry
 from homeassistant.const import (
@@ -218,6 +219,24 @@ async def async_setup(hass: HomeAssistant, config: ConfigType) -> bool:
 
     register_websocket_api(hass)
 
+    url = "/api/panel_custom/knx_ui"
+    hass.http.register_static_path(url, get_knx_ui())
+    hass.components.frontend.async_register_built_in_panel(
+        component_name="custom",
+        sidebar_title="KNX UI",
+        sidebar_icon="mdi:earth",
+        frontend_url_path="knx_ui",
+        config={
+            "_panel_custom": {
+                "name": "knx-custom-panel",
+                "embed_iframe": False,
+                "trust_external": False,
+                "js_url": url,
+            }
+        },
+        require_admin=True,
+    )
+
     return True
 
 
diff --git a/homeassistant/components/knx/manifest.json b/homeassistant/components/knx/manifest.json
index 266eceaace..9ef9cc8090 100644
--- a/homeassistant/components/knx/manifest.json
+++ b/homeassistant/components/knx/manifest.json
@@ -3,7 +3,7 @@
   "name": "KNX",
   "config_flow": true,
   "documentation": "https://www.home-assistant.io/integrations/knx",
-  "requirements": ["xknx==0.22.1"],
+  "requirements": ["xknx==0.22.1", "xknx-custom-panel==1.6.6"],
   "codeowners": ["@Julius2342", "@farmio", "@marvin-w"],
   "quality_scale": "platinum",
   "iot_class": "local_push",
diff --git a/requirements_all.txt b/requirements_all.txt
index 35a231a8cd..9c939eddd6 100644
--- a/requirements_all.txt
+++ b/requirements_all.txt
@@ -2484,6 +2484,7 @@ xiaomi-ble==0.9.0
 
 # homeassistant.components.knx
 xknx==0.22.1
+xknx-custom-panel==1.6.6
 
 # homeassistant.components.bluesound
 # homeassistant.components.fritz
diff --git a/requirements_test_all.txt b/requirements_test_all.txt
index 011c93291e..e73a78b21b 100644
--- a/requirements_test_all.txt
+++ b/requirements_test_all.txt
@@ -1682,6 +1682,7 @@ xiaomi-ble==0.9.0
 
 # homeassistant.components.knx
 xknx==0.22.1
+xknx-custom-panel==1.6.6
 
 # homeassistant.components.bluesound
 # homeassistant.components.fritz